Note: Screenshots above go in order of Enabled then Disabled.
A personal preset that I use on my GTX 970 for use in taking artistic screenshots, requires high end specs to use as a gameplay preset, does not use SMAA/FXAA or Ambient Occlusion or DoF, although they can all be activated with the mediator. simply load Mediator whilst in game change settings and apply, works whilst ingame. In game use all maxed settings along with Temporal Anti-aliasing.
Installation:
Extract archive contents to Fallout 4 steamapps installation folder
Requirements:
AMD R9 290+ / 380-390+ series
Nvidia GTX 770-780+ / 960-970-980+
Thanks to Crosire for the incredible Reshade project